Veröffentlichungen

2019

1: Mörs K, Wagner N, Sturm R, Störmann P, Vollrath JT, Marzi I, Relja B. Enhanced pro-inflammatory response and higher mortality rates in geriatric trauma patients. Eur J Trauma Emerg Surg. 2019 Dec 24. doi: 10.1007/s00068-019-01284-1. [Epub ahead of print] PubMed PMID: 31875239

2: Voth M, Lustenberger T, Relja B, Marzi I.Is I-FABP not only a marker for the detection abdominal injury but also of hemorrhagic shock in severely injured trauma patients? World J Emerg Surg. 2019 Nov 21;14:49. doi: 10.1186/s13017-019-0267-9 . eCollection 2019. PMID: 31832083 Free PMC article.

3: Leiblein M, Koch E, Winkenbach A, Schaible A, Nau C, Büchner H, Schröder K, Marzi I, Henrich D. Size matters: Effect of granule size of the bone graft substitute (Herafill®) on bone healing using Masquelet's induced membrane in a critical size defect model in the rat's femur. J Biomed Mater Res B Appl Biomater. 2020 May;108(4):1469-1482. doi: 10.1002/jbm.b.34495 . Epub 2019 Nov 13. PMID: 31721435

4: Störmann P, Osinloye W, Freiman TM, Seifert V, Marzi I, Lustenberger T. Early Chemical Thromboprophylaxis Does not Increase the Risk of Intracranial Hematoma Progression in Patients with Isolated Severe Traumatic Brain Injury. World J Surg. 2019 Nov;43(11):2804-2811. doi: 10.1007/s00268-019-05072-1. PMID: 31267142

5: Xu B, Janicova A, Vollrath JT, Störmann P, Martin L, Marzi I, Wutzler S, Hildebrand F, Ehnert S, Relja B. Club cell protein 16 in sera from trauma patients modulates neutrophil migration and functionality via CXCR1 and CXCR2. Mol Med. 2019 Oct 30;25(1):45. doi: 10.1186/s10020-019-0115-0. PMID: 31666007 Free PMC article.

6: Mühlenfeld N, Söhling N, Marzi I, Pieper M, Paule E, Reif PS, Strzelczyk A, Verboket RD, Willems LM. Fractures in Parkinson's Disease: injury patterns, hospitalization, and therapeutic aspects. Eur J Trauma Emerg Surg. 2019 Oct 14. doi: 10.1007/s00068-019-01240-z . Online ahead of print. PMID: 31608417

7: Janicova A, Becker N, Xu B, Wutzler S, Vollrath JT, Hildebrand F, Ehnert S, Marzi I, Störmann P, Relja B. Endogenous Uteroglobin as Intrinsic Anti-inflammatory Signal Modulates Monocyte and Macrophage Subsets Distribution Upon Sepsis Induced Lung Injury. Front Immunol. 2019 Oct 1;10:2276. doi: 10.3389/fimmu.2019.02276 . eCollection 2019. PMID: 31632392 Free PMC article.

8: Wagner N, Relja B, Lustenberger T, Leiblein M, Wutzler S, Lefering R, Marzi I; TraumaRegister DGU3. The influence of alcohol on the outcome of trauma patients: a matched-pair analysis of the TraumaRegister DGU^®. Eur J Trauma Emerg Surg. 2020 Jun;46(3):463-472. doi: 10.1007/s00068-019-01231-0 . Epub 2019 Sep 25. PMID: 31555876

9: Meybohm P, Kohlhof H, Wirtz DC, Marzi I, Füllenbach C, Choorapoikayil S, Wittmann M, Marschall U, Thoma J, Schwendner K, Stark P, Raadts A, Friedrich J, Weigt H, Friederich P, Huber J, Gutjahr M, Schmitt E, Zacharowski K. Preoperative Anaemia in Primary Hip and Knee Arthroplasty. Z Orthop Unfall. 2020 Apr;158(2):194-200. doi: 10.1055/a-0974-4115 . Epub 2019 Sep 18. PMID: 31533166

10: Lackner I, Weber B, Baur M, Haffner-Luntzer M, Eiseler T, Fois G, Gebhard F, Relja B, Marzi I, Pfeifer R, Halvachizadeh S, Lipiski M, Cesarovic N, Pape HC, Kalbitz M; TREAT Research Group. Midkine Is Elevated After Multiple Trauma and Acts Directly on Human Cardiomyocytes by Altering Their Functionality and Metabolism. Front Immunol. 2019 Aug 21;10:1920. doi: 10.3389/fimmu.2019.01920 . eCollection 2019. PMID: 31552013

11: Verboket R, Verboket C, Schöffski O, Tlatlik J, Marzi I, Nau C. Costs and proceeds from patients admitted via the emergency room with mild craniocerebral trauma. Unfallchirurg. 2019 Aug;122(8):618-625. doi: 10.1007/s00113-018-0566-8. PMID: 30306215

12: Relja B, Huber-Lang M, van Griensven M, Hildebrand F, Maegele M, Nienaber U, Brucker DP, Sturm R, Marzi I. A nationwide fluidics biobank of polytraumatized patients: implemented by the Network "Trauma Research" (NTF) as an expansion to the TraumaRegister DGU^® of the German Trauma Society (DGU). Eur J Trauma Emerg Surg. 2020 Jun;46(3):499-504. doi: 10.1007/s00068-019-01193-3 . Epub 2019 Jul 19. PMID: 31324937

13: Verboket R, Söhling N, Schmitz L, Lustenberger T, Nau C, Marzi I. Violence in the emergency department of a maximum care hospital. Chirurg. 2019 Jul;90(7):570-575. doi: 10.1007/s00104-018-0778-z. PMID: 30617469

14: Wagner N, Dieteren S, Franz N, Köhler K, Perl M, Marzi I, Relja B. Alcohol‑induced attenuation of post‑traumatic inflammation is not necessarily liver‑protective following trauma/hemorrhage. Int J Mol Med. 2019 Sep;44(3):1127-1138. doi: 10.3892/ijmm.2019.4259 . Epub 2019 Jun 27. PMID: 31257463

15: Störmann P, Becker N, Vollrath JT, Köhler K, Janicova A, Wutzler S, Hildebrand F, Marzi I, Relja B. Early Local Inhibition of Club Cell Protein 16 Following Chest Trauma Reduces Late Sepsis-Induced Acute Lung Injury. J Clin Med. 2019 Jun 22;8(6):896. doi: 10.3390/jcm8060896. PMID: 31234556

16: Arsalan-Werner A, Sterz J, Stefanescu MC, Janko M, Sommer K, Frank J, Marzi I, Sauerbier M, Rüsseler M. The importance of hand surgery in the German Medical Licensing Examination. Handchir Mikrochir Plast Chir. 2019 Jun;51(3):193-198. doi: 10.1055/a-0915-9710 . Epub 2019 Jun 5. PMID: 31167280

17: Lustenberger T, Leonardy R, Marzi I, Frank J. Outcome after surgical treatment of complex elbow fractures: a single-center follow-up study. Eur J Trauma Emerg Surg. 2019 May 21. doi: 10.1007/s00068-019-01157-7 . Online ahead of print. PMID: 31115614

18: Leiblein M, Verboket R, Marzi I, Wagner N, Nau C. Nonunions of the humerus - Treatment concepts and results of the last five years. Chin J Traumatol. 2019 Aug;22(4):187-195. doi: 10.1016/j.cjtee.2019.04.002 . Epub 2019 May 4. PMID: 31109830

19: Leiblein M, Henrich D, Fervers F, Kontradowitz K, Marzi I, Seebach C. Do antiosteoporotic drugs improve bone regeneration in vivo? Eur J Trauma Emerg Surg. 2020 Apr;46(2):287-299. doi: 10.1007/s00068-019-01144-y . Epub 2019 Apr 26. PMID: 31028428

20: Yel I, Booz C, Albrecht MH, Gruber-Rouh T, Polkowski C, Jacobi M, Lenga L, Schulz M, Frank J, Marzi I, Vogl TJ, Eichler K, Kaltenbach B. Optimization of image quality and radiation dose using different cone-beam CT exposure parameters. Eur J Radiol. 2019 Jul;116:68-75. doi: 10.1016/j.ejrad.2019.04.005 . Epub 2019 Apr 22. PMID: 31153576

21: Zabel J, Sterz J, Hoefer SH, Stefanescu MC, Lehmann M, Sakmen DK, Marzi I, Ruesseler M. The Use of Teaching Associates for Knee and Shoulder Examination: A Comparative Effectiveness Analysis. J Surg Educ. 2019 Sep-Oct;76(5):1440-1449. doi: 10.1016/j.jsurg.2019.03.006 . Epub 2019 Apr 5. PMID: 30956084

22: Störmann P, Becker N, Künnemeyer L, Wutzler S, Vollrath JT, Lustenberger T, Hildebrand F, Marzi I, Relja B. Contributing factors in the development of acute lung injury in a murine double hit model. Eur J Trauma Emerg Surg. 2020 Feb;46(1):21-30. doi: 10.1007/s00068-019-01121-5 . Epub 2019 Apr 1. PMID: 30937460

23: Franz N, Dieteren S, Köhler K, Mörs K, Sturm R, Marzi I, Perl M, Relja B, Wagner N. Alcohol Binge Reduces Systemic Leukocyte Activation and Pulmonary PMN Infiltration After Blunt Chest Trauma and Hemorrhagic Shock. Franz N, Dieteren S, Köhler K, Mörs K, Sturm R, Marzi I, Perl M, Relja B, Wagner N. Inflammation. 2019 Apr;42(2):690-701. doi: 10.1007/s10753-018-0927-z .PMID: 30411212

24: Wutzler S, Bläsius FM, Störmann P, Lustenberger T, Frink M, Maegele M, Weuster M, Bayer J, Caspers M, Seekamp A, Marzi I, Andruszkow H, Hildebrand F. Pneumonia in severely injured patients with thoracic trauma: results of a retrospective observational multi-centre study. Scand J Trauma Resusc Emerg Med. 2019 Mar 14;27(1):31. doi: 10.1186/s13049-019-0608-4 . PMID: 30871601

25: Störmann P, Wagner N, Köhler K, Auner B, Simon TP, Pfeifer R, Horst K, Pape HC, Hildebrand F, Wutzler S, Marzi I, Relja B. Monotrauma is associated with enhanced remote inflammatory response and organ damage, while polytrauma intensifies both in porcine trauma model. Eur J Trauma Emerg Surg. 2020 Feb;46(1):31-42. doi: 10.1007/s00068-019-01098-1 . Epub 2019 Mar 12. PMID: 30864051

26: Maegele M, Lefering R, Sakowitz O, Kopp MA, Schwab JM, Steudel WI, Unterberg A, Hoffmann R, Uhl E, Marzi I.The Incidence and Management of Moderate to Severe Head Injury. Dtsch Arztebl Int. 2019 Mar 8;116(10):167-173. doi: 10.3238/arztebl.2019.0167. PMID: 30995953

27: Eguchi A, Franz N, Kobayashi Y, Iwasa M, Wagner N, Hildebrand F, Takei Y, Marzi I, Relja B. Circulating Extracellular Vesicles and Their miR "Barcode" Differentiate Alcohol Drinkers With Liver Injury and Those Without Liver Injury in Severe Trauma Patients. Front Med (Lausanne). 2019 Feb 25;6:30. doi: 10.3389/fmed.2019.00030 . eCollection 2019. PMID: 30859103

28: Marzi I. Focus on non-union of fractures. Eur J Trauma Emerg Surg. 2019 Feb;45(1):1-2. doi: 10.1007/s00068-019-01079-4 . PMID: 30706111

29: Sommer K, Jakob H, Badjlan F, Henrich D, Frank J, Marzi I, Sander AL. 11,12 and 14,15 epoxyeicosatrienoic acid rescue deteriorated wound healing in ischemia. PLoS One. 2019 Jan 16;14(1):e0209158. doi: 10.1371/journal.pone.0209158 . eCollection 2019. PMID: 30650075

30: Marzi I, Lustenberger T, Störmann P, Mörs K, Wagner N, Wutzler S. Increasing overhead ressources of the trauma room. Unfallchirurg. 2019 Jan;122(1):53-58. doi: 10.1007/s00113-018-0484-9 . PMID: 29556688

31: Verboket R, Herrera-Vizcaíno C, Thorwart K, Booms P, Bellen M, Al-Maawi S, Sader R, Marzi I, Henrich D, Ghanaati S. Influence of concentration and preparation of platelet rich fibrin on human bone marrow mononuclear cells (in vitro). Platelets. 2019;30(7):861-870. doi: 10.1080/09537104.2018.1530346 . Epub 2018 Oct 25. PMID: 30359164

32: Verboket RD, Söhling N, Marzi I, Paule E, Knake S, Rosenow F, Strzelczyk A, Willems LM. Prevalence, risk factors and therapeutic aspects of injuries and accidents in women with epilepsy. Eur J Trauma Emerg Surg. 2019 Jun;45(3):375-381. doi: 10.1007/s00068-018-1030-8 . Epub 2018 Oct 11. PMID: 30310959

33: Ruesseler M, Tomczak M, Thrun M, Pfau S, Marzi I, Sterz J. The Influence of the Instructional Approach on Acquiring Clinical Skills in Surgery: A Comparative Effectiveness Study. J Surg Educ. 2019 Jan-Feb;76(1):140-149. doi: 10.1016/j.jsurg.2018.07.008 . Epub 2018 Aug 16. PMID: 30122637

34: Janko M, Dietz K, Rachor J, Sahm J, Schroder K, Schaible A, Nau C, Seebach C, Marzi I, Henrich D. Improvement of Bone Healing by Neutralization of microRNA-335-5p, but not by Neutralization of microRNA-92A in Bone Marrow Mononuclear Cells Transplanted into a Large Femur Defect of the Rat. Tissue Eng Part A. 2019 Jan;25(1-2):55-68. doi: 10.1089/ten.TEA.2017.0479 . Epub 2018 Apr 23. PMID: 29652605

35: Störmann P, Kupsch J, Kontradowitz K, Leiblein M, Verboket R, Seebach C, Marzi I, Henrich D, Nau C. Cultivation of EPC and co-cultivation with MSC on β-TCP granules in vitro is feasible without fibronectin coating but influenced by scaffolds' design. Eur J Trauma Emerg Surg. 2019 Jun;45(3):527-538. doi: 10.1007/s00068-018-0935-6 . Epub 2018 Mar 9. PMID: 29523894

36: Malkomes P, Störmann P, El Youzouri H, Wutzler S, Marzi I, Vogl T, Bechstein WO, Habbe N. Characteristics and management of penetrating abdominal injuries in a German level I trauma center. Eur J Trauma Emerg Surg. 2019 Apr;45(2):315-321. doi: 10.1007/s00068-018-0911-1 . Epub 2018 Jan 22. PMID: 29356844

2018

1: Franz N, Dieteren S, Köhler K, Mörs K, Sturm R, Marzi I, Perl M, Relja B, Wagner N. Alcohol Binge Reduces Systemic Leukocyte Activation and Pulmonary PMN Infiltration After Blunt Chest Trauma and Hemorrhagic Shock. Inflammation. 2018 Nov 9. doi: 10.1007/s10753-018-0927-z. [Epub ahead of print] PubMed PMID:30411212.

2: Verboket R, Herrera-Vizcaíno C, Thorwart K, Booms P, Bellen M, Al-Maawi S, Sader R, Marzi I, Henrich D, Ghanaati S. Influence of concentration and preparation of platelet rich fibrin on human bone marrow mononuclear cells (in vitro). Platelets. 2018 Oct 25:1-10. doi: 0.1080/09537104.2018.1530346. [Epub ahead of print] PubMed PMID: 30359164.

3: Verboket RD, Söhling N, Marzi I, Paule E, Knake S, Rosenow F, Strzelczyk A, Willems LM. Prevalence, risk factors and therapeutic aspects of injuries and accidents in women with epilepsy. Eur J Trauma Emerg Surg. 2018 Oct 11. doi: 10.1007/s00068-018-1030-8. [Epub ahead of print] PubMed PMID: 30310959.

4: Verboket R, Verboket C, Schöffski O, Tlatlik J, Marzi I, Nau C. [Costs and proceeds from patients admitted via the emergency room with mild craniocerebral trauma]. Unfallchirurg. 2018 Oct 10. doi: 10.1007/s00113-018-0566-8. [Epub ahead of print] German. PubMed PMID: 30306215.

5: Sander AL, Leiblein M, Sommer K, Marzi I, Schneidmüller D, Frank J. Epidemiology and treatment of distal radius fractures: current concept based on fracture severity and not on age. Eur J Trauma Emerg Surg. 2018 Oct 1. doi: 10.1007/s00068-018-1023-7. [Epub ahead of print] PubMed PMID: 30276724.

6: Verboket R, Leiblein M, Seebach C, Nau C, Janko M, Bellen M, Bönig H, Henrich D, Marzi I. Autologous cell-based therapy for treatment of large bone defects: from bench to bedside. Eur J Trauma Emerg Surg. 2018 Oct;44(5):649-665. doi: 10.1007/s00068-018-0906-y. Epub 2018 Jan 19. Review. PubMed PMID: 29352347; PubMed Central PMCID: PMC6182650.

7: Nau C, Simon S, Schaible A, Seebach C, Schröder K, Marzi I, Henrich D. Influence of the induced membrane filled with syngeneic bone and regenerative cells on bone healing in a critical size defect model of the rat's femur. Injury. 2018 Oct;49(10):1721-1731. doi: 10.1016/j.injury.2018.06.041. Epub 2018 Jul 2. PubMed PMID: 30244700.

8: Leiblein M, Ponelies N, Johnson T, Marzi J, Kontradowitz K, Geiger E, Marzi I, Henrich D. Increased extracellular ubiquitin in surgical wound fluid provides a chemotactic signal for myeloid dendritic cells. Eur J Trauma Emerg Surg. 2018 Aug 30. doi: 10.1007/s00068-018-1001-0. [Epub ahead of print] PubMed PMID: 30159662.

9: Ruesseler M, Tomczak M, Thrun M, Pfau S, Marzi I, Sterz J. The Influence of the Instructional Approach on Acquiring Clinical Skills in Surgery: A Comparative Effectiveness Study. J Surg Educ. 2018 Aug 16. pii: S1931-7204(18)30313-1. doi: 10.1016/j.jsurg.2018.07.008. [Epub ahead of print] PubMed PMID: 30122637.

10: Sterz J, Britz V, Münzberg M, Kadmon M, Schleicher I, Meder A, Kamp R, Janko M, Marzi I, Rüsseler M. [Weighting of Orthopaedics & Trauma Surgery in the Medical State Examination - Comparison of the Written Examination with the National Catalogue of Learning Objectives in Surgery]. Z Orthop Unfall. 2018 Aug;156(4):393-398. doi: 10.1055/s-0044-100930. Epub 2018 Mar 9. German. PubMed PMID: 29523015.

11: Balogh ZJ, Marzi I. Novel concepts related to inflammatory complications in polytrauma. Eur J Trauma Emerg Surg. 2018 Jun;44(3):299-300. doi: 10.1007/s00068-018-0964-1. PubMed PMID: 29846766.

12: Relja B, Mörs K, Marzi I. Danger signals in trauma. Eur J Trauma Emerg Surg. 2018 Jun;44(3):301-316. doi: 10.1007/s00068-018-0962-3. Epub 2018 May 4. Review. PubMed PMID: 29728738; PubMed Central PMCID: PMC6002466.

13: Mauffrey C, Hak DJ, Giannoudis P, Alt V, Nau C, Marzi I, Augat P, Oh JK, Frank J, Mavrogenis A, Flecher X, Argenson JN, Gavaskar A, Rojas D, Bedeir YH; From the ORS/ISFR expert group on Tibial bone defects. Treatment of infection following intramedullary nailing of tibial shaft fractures-results of the ORS/ISFR expert group survey. Int Orthop. 2018 May 3. doi: 10.1007/s00264-018-3964-1. [Epub ahead of print] PubMed PMID: 29725735.

14: Sander AL, Sommer K, Eichler K, Marzi I, Frank J. [Mediocarpal instability of the wrist]. Unfallchirurg. 2018 May;121(5):365-372. doi: 10.1007/s00113-018-0476-9. Review. German. PubMed PMID: 29536137.

15: Mörs K, Kany S, Hörauf JA, Wagner N, Neunaber C, Perl M, Marzi I, Relja B. Suppression of the interleukin-1ß-induced inflammatory response of human Chang liver cells by acute and subacute exposure to alcohol: an in vitro study. Croat Med J. 2018 Apr 30;59(2):46-55. PubMed PMID: 29740988; PubMed Central PMCID: PMC5941294.

16: Janko M, Dietz K, Rachor J, Sahm J, Schroder K, Schaible A, Nau C, Seebach C, Marzi I, Henrich D. Improvement of Bone Healing by Neutralization of microRNA-335-5p, but not by Neutralization of microRNA-92A in Bone Marrow Mononuclear Cells Transplanted into a Large Femur Defect of the Rat. Tissue Eng Part A. 2018 Apr 23. doi: 10.1089/ten.TEA.2017.0479. [Epub ahead of print] PubMed PMID: 29652605.

17: Polytrauma Guideline Update Group. Level 3 guideline on the treatment of patients with severe/multiple injuries : AWMF Register-Nr. 012/019. Eur J Trauma Emerg Surg. 2018 Apr;44(Suppl 1):3-271. doi: 10.1007/s00068-018-0922-y. PubMed PMID: 29654333.

18: Bouillon B, Marzi I. The updated German "Polytrauma - Guideline": an extensive literature evaluation and treatment recommendation for the care of the critically injured patient. Eur J Trauma Emerg Surg. 2018 Apr;44(Suppl 1):1. doi: 10.1007/s00068-018-0949-0. PubMed PMID: 29623341.

19: Leiblein M, Marzi I, Sander AL, Barker JH, Ebert F, Frank J. Necrotizing fasciitis: treatment concepts and clinical results. Eur J Trauma Emerg Surg. 2018 Apr;44(2):279-290. doi: 10.1007/s00068-017-0792-8. Epub 2017 May 8. PubMed PMID: 28484782.

20: Marzi I, Lustenberger T, Störmann P, Mörs K, Wagner N, Wutzler S. [Increasing overhead ressources of the trauma room]. Unfallchirurg. 2018 Mar 19. doi: 10.1007/s00113-018-0484-9. [Epub ahead of print] German. PubMed PMID: 29556688.

21: Leppik L, Zhihua H, Mobini S, Thottakkattumana Parameswaran V, Eischen-Loges M, Slavici A, Helbing J, Pindur L, Oliveira KMC, Bhavsar MB, Hudak L, Henrich D, Barker JH. Combining electrical stimulation and tissue engineering to treat large bone defects in a rat model. Sci Rep. 2018 Apr 20;8(1):6307. doi: 10.1038/s41598-018-24892-0. PubMed PMID: 29679025; PubMed Central PMCID:

PMC5910383.

22: Duecker R, Baer P, Eickmeier O, Strecker M, Kurz J, Schaible A, Henrich D, Zielen S, Schubert R. Oxidative stress-driven pulmonary inflammation and fibrosis in a mouse model of human ataxia-telangiectasia. Redox Biol. 2018 Apr;14:645-655. doi: 10.1016/j.redox.2017.11.006. Epub 2017 Nov 10. PubMed PMID: 29172151; PubMed Central PMCID: PMC5975220.

2017

1: Kalbitz M, Schwarz S, Weber B, Bosch B, Pressmar J, Hoenes FM, Braun CK, Horst K, Simon TP, Pfeifer R, Störmann P, Hummler H, Gebhard F, Pape HC, Huber-Lang M, Hildebrand F; TREAT Research Group. Cardiac Depression in Pigs after Multiple Trauma - Characterization of Posttraumatic Structural and Functional Alterations. Sci Rep. 2017 Dec 19;7(1):17861. doi: 10.1038/s41598-017-18088-1. PubMed PMID: 29259232; PubMed Central PMCID: PMC5736586.

2: Störmann P, Marzi I, Wutzler S. Rotational therapy in thoracic injuries: what is the evidence? Curr Opin Crit Care. 2017 Dec;23(6):527-532. doi: 10.1097/MCC.0000000000000467. Review. PubMed PMID: 29035924.

3: Störmann P, Auner B, Schimunek L, Serve R, Horst K, Simon TP, Pfeifer R, Köhler K, Hildebrand F, Wutzler S, Pape HC, Marzi I, Relja B; This study was performed within the study consortium of the TREAT Research Group. Leukotriene B4 indicates lung injury and on-going inflammatory changes after severe trauma in a porcine long-term model. Prostaglandins Leukot Essent Fatty Acids. 2017 Dec;127:25-31. doi: 10.1016/j.plefa.2017.09.014. Epub 2017 Sep 22. PubMed PMID: 29156155.

4: Voth M, Duchene M, Auner B, Lustenberger T, Relja B, Marzi I. I-FABP is a Novel Marker for the Detection of Intestinal Injury in Severely Injured Trauma Patients. World J Surg. 2017 Dec;41(12):3120-3127. doi: 10.1007/s00268-017-4124-2. PubMed PMID: 28721572.

5: Schimunek L, Serve R, Teuben MPJ, Störmann P, Auner B, Woschek M, Pfeifer R, Horst K, Simon TP, Kalbitz M, Sturm R, Pape HC, Hildebrand F, Marzi I, Relja B. Early decreased TLR2 expression on monocytes is associated with their reduced phagocytic activity and impaired maturation in a porcine polytrauma model. PLoS One. 2017 Nov 10;12(11):e0187404. doi: 10.1371/journal.pone.0187404. eCollection 2017. PubMed PMID: 29125848; PubMed Central PMCID: PMC5681268.

6: Voth M, Kremer L, Marzi I. [Fractures of the lower extremities in childhood : Part 2: lower leg and ankle fractures]. Chirurg. 2017 Nov;88(11):983-994. doi: 10.1007/s00104-017-0515-z. Review. German. PubMed PMID: 29026917.

7: Störmann P, Lustenberger T, Relja B, Marzi I, Wutzler S. Role of biomarkers in acute traumatic lung injury. Injury. 2017 Nov;48(11):2400-2406. doi: 10.1016/j.injury.2017.08.041. Epub 2017 Aug 24. Review. PubMed PMID: 28888717.

8: Marzi I. [Trauma surgery - Orthopedics and trauma surgery - Surgery]. Chirurg. 2017 Oct;88(10):817-818. doi: 10.1007/s00104-017-0498-9. German. PubMed PMID: 28951945.

9: Kremer L, Voth M, Marzi I. [Fractures of the lower extremities in childhood : Part 1: fractures of the thigh and in the proximity of the knee]. Chirurg. 2017 Oct;88(10):891-902. doi: 10.1007/s00104-017-0507-z. German. PubMed PMID: 28929265.

10: Voth M, Lustenberger T, Frank J, Marzi I. [Pediatric finger and hand injuries : An epidemiological study]. Chirurg. 2017 Oct;88(10):871-878. doi: 10.1007/s00104-017-0499-8. German. PubMed PMID: 28819815.

11: Voth M, Lustenberger T, Auner B, Frank J, Marzi I. What injuries should we expect in the emergency room? Injury. 2017 Oct;48(10):2119-2124. doi: 10.1016/j.injury.2017.07.027. Epub 2017 Jul 27. PubMed PMID: 28778731.

12: Vogl TJ, Eichler K, Marzi I, Wutzler S, Zacharowski K, Frellessen C. [Imaging techniques in modern trauma diagnostics]. Med Klin Intensivmed Notfmed. 2017 Oct;112(7):643-657. doi: 10.1007/s00063-017-0359-9. German. PubMed PMID: 28936574.

13: Vogl TJ, Eichler K, Marzi I, Wutzler S, Zacharowski K, Frellessen C. [Imaging techniques in modern trauma diagnostics]. Radiologe. 2017 Oct;57(10):853-868. doi: 10.1007/s00117-017-0296-x. German. PubMed PMID: 28819674.

14: Meurer A, Marzi I, Beck A. Bewegung ist Leben. Z Orthop Unfall. 2017 Oct;155(5):526. doi: 10.1055/s-0043-117899. Epub 2017 Oct 19. German. PubMed PMID: 29050053.

15: Hildebrand F, Grässel S, Marzi I, Meurer A, Nerlich M, Loibl M. [Cooperation of the German Society of Orthopaedics and Trauma (DGOU) and the Orthopaedic Research Society (ORS)]. Z Orthop Unfall. 2017 Oct;155(5):515-516. doi: 10.1055/s-0043-116849. Epub 2017 Oct 19. German. PubMed PMID: 29050047.

16: Wagner N, Franz N, Dieteren S, Perl M, Mörs K, Marzi I, Relja B. Acute Alcohol Binge Deteriorates Metabolic and Respiratory Compensation Capability After Blunt Chest Trauma Followed by Hemorrhagic Shock-A New Research Model. Alcohol Clin Exp Res. 2017 Sep;41(9):1559-1567. doi: 10.1111/acer.13446. Epub 2017 Aug 9. PubMed PMID: 28715125.

17: Coccolini F, Montori G, Catena F, Kluger Y, Biffl W, Moore EE, Reva V, Bing C, Bala M, Fugazzola P, Bahouth H, Marzi I, Velmahos G, Ivatury R, Soreide K, Horer T, Ten Broek R, Pereira BM, Fraga GP, Inaba K, Kashuk J, Parry N, Masiakos PT, Mylonas KS, Kirkpatrick A, Abu-Zidan F, Gomes CA, Benatti SV, Naidoo N, Salvetti F, Maccatrozzo S, Agnoletti V, Gamberini E, Solaini L, Costanzo A, Celotti A, Tomasoni M, Khokha V, Arvieux C, Napolitano L, Handolin L, Pisano M, Magnone S, Spain DA, de Moya M, Davis KA, De Angelis N, Leppaniemi A, Ferrada P, Latifi R, Navarro DC, Otomo Y, Coimbra R, Maier RV, Moore F, Rizoli S, Sakakushev B, Galante JM, Chiara O, Cimbanassi S, Mefire AC, Weber D, Ceresoli M, Peitzman AB, Wehlie L, Sartelli M, Di Saverio S, Ansaloni L. Splenic trauma: WSES classification and guidelines for adult and pediatric patients. World J Emerg Surg. 2017 Aug 18;12:40. doi: 10.1186/s13017-017-0151-4. eCollection 2017. Review. PubMed PMID: 28828034; PubMed Central PMCID: PMC5562999.

18: Wicker S, Wutzler S, Marzi I, Rabenau HF. Akute Hepatitis C eines Kardiochirurgen nach Nadelstichverletzung – ein Fall von „Murphyʼs Law“? Zentralbl Chir. 2017 Aug;142(4):428-431. doi: 10.1055/s-0042-110659. Epub 2016 Jul 7. German. PubMed PMID: 27389576.

19: Perez-Abadia G, Janko M, Pindur L, Sauerbier M, Barker JH, Joshua I, Marzi I, Frank J. Frankfurt microsurgery course: the first 175 trainees. Eur J Trauma Emerg Surg. 2017 Jun;43(3):377-386. doi: 10.1007/s00068-016-0759-1. Epub 2017 Feb 4. PubMed PMID: 28161793; PubMed Central PMCID: PMC5487763.

20: Vogl TJ, Eichler K, Marzi I, Wutzler S, Zacharowski K, Frellessen C. [Imaging techniques in modern trauma diagnostics]. Unfallchirurg. 2017 May;120(5):417-431. doi: 10.1007/s00113-017-0352-z. Review. German. PubMed PMID: 28455618.

2016

1: Wutzler S, Sturm K, Lustenberger T, Wyen H, Zacharowksi K, Marzi I, Bingold T. Kinetic therapy in multiple trauma patients with severe thoracic trauma: a treatment option to reduce ventilator time and improve outcome. Eur J Trauma Emerg Surg. 2017 Apr;43(2):155-161. doi: 10.1007/s00068-016-0692-3. Epub 2016 Jun 6. PubMed PMID: 27272916.

2: Sturm R, Heftrig D, Mörs K, Wagner N, Kontradowitz K, Jurida K, Marzi I, Relja B. Phagocytizing activity of PMN from severe trauma patients in different post-traumatic phases during the 10-days post-injury course. Immunobiology. 2017 Feb;222(2):301-307. doi: 10.1016/j.imbio.2016.09.010. Epub 2016 Sep 29. PubMed PMID: 27745899.

3: Horst K, Simon TP, Pfeifer R, Teuben M, Almahmoud K, Zhi Q, Santos SA, Wembers CC, Leonhardt S, Heussen N, Störmann P, Auner B, Relja B, Marzi I, Haug AT, van Griensven M, Kalbitz M, Huber-Lang M, Tolba R, Reiss LK, Uhlig S, Marx G, Pape HC, Hildebrand F. Characterization of blunt chest trauma in a long-term porcine model of severe multiple trauma. Sci Rep. 2016 Dec 21;6:39659. doi: 10.1038/srep39659. PubMed PMID: 28000769; PubMed Central PMCID: PMC5175194.

4: Relja B, Taraki R, Teuben MP, Mörs K, Wagner N, Wutzler S, Hildebrand F, Perl M, Marzi I. Sera from severe trauma patients with pneumonia and without infectious complications have differential effects on neutrophil biology. BMC Pulm Med. 2016 Dec 1;16(1):171. PubMed PMID: 27905913; PubMed Central PMCID: PMC5131406.

5: Störmann P, Gartner K, Wyen H, Lustenberger T, Marzi I, Wutzler S. Epidemiology and outcome of penetrating injuries in a Western European urban region. Eur J Trauma Emerg Surg. 2016 Dec;42(6):663-669. Epub 2016 Jan 13. PubMed PMID: 26762313.

6: Lustenberger T, Walcher F, Lefering R, Schweigkofler U, Wyen H, Marzi I, Wutzler S; TraumaRegister DGU. The Reliability of the Pre-hospital Physical Examination of the Pelvis: A Retrospective, Multicenter Study. World J Surg. 2016 Dec;40(12):3073-3079. doi: 10.1007/s00268-016-3647-2. PubMed PMID: 27460140.

7: Meurer A, Marzi I, Beck A, Mutschler M, Grimaldi G. Junges Forum O&U – Summer School der DGOU und des BVOU. Z Orthop Unfall. 2016 Dec;154(6):554. Epub 2016 Dec 14. German. PubMed PMID: 27975348.

8: Seebach C, Henrich D, Meier S, Nau C, Bonig H, Marzi I. Safety and feasibility of cell-based therapy of autologous bone marrow-derived mononuclear cells in plate-stabilized proximal humeral fractures in humans. J Transl Med. 2016 Nov 15;14(1):314. PubMed PMID: 27846890; PubMed Central PMCID: PMC5111224.

9: Wutzler S, Marzi I. Routine total-body CT for trauma room patients-life saver or needless radiation exposure? J Thorac Dis. 2016 Nov;8(11):3040-3041. doi: 10.21037/jtd.2016.11.15. PubMed PMID: 28066577; PubMed Central PMCID: PMC5179437.

10: Fischer S, Vogl TJ, Kresing M, Marzi I, Zangos S, Mack MG, Eichler K. Minimally invasive screw fixation of fractures in the thoracic spine: CT-controlled pre-surgical guidewire implantation in routine clinical practice. Clin Radiol. 2016 Oct;71(10):997-1004. doi: 10.1016/j.crad.2016.06.112. Epub 2016 Jul 15. PubMed PMID: 27426675.

11: Henrich D, Seebach C, Nau C, Basan S, Relja B, Wilhelm K, Schaible A, Frank J, Barker J, Marzi I. Establishment and characterization of the Masquelet induced membrane technique in a rat femur critical-sized defect model. J Tissue Eng Regen Med. 2016 Oct;10(10):E382-E396. doi: 10.1002/term.1826. Epub 2013 Nov 8. PubMed PMID: 24668794.

12: Wagner N, Akbarpour A, Mörs K, Voth M, Störmann P, Auner B, Lehnert M, Marzi I, Relja B. Alcohol Intoxication Reduces Systemic Interleukin-6 Levels and Leukocyte Counts After Severe TBI Compared With Not Intoxicated TBI Patients. Shock. 2016 Sep;46(3):261-9. doi: 10.1097/SHK.0000000000000620. PubMed PMID: 27058046.

13: Mörs K, Braun O, Wagner N, Auner B, Voth M, Störmann P, Wutzler S, Marzi I,Relja B. Influence of gender on systemic IL-6 levels, complication rates and outcome after major trauma. Immunobiology. 2016 Aug;221(8):904-10. doi: 10.1016/j.imbio.2016.03.005. Epub 2016 Mar 18. PubMed PMID: 27017325.

14: Wicker S, Rabenau HF, Scheller B, Marzi I, Wutzler S. [Prevalence of blood-borne pathogens among 275 trauma patients : A prospective observational study]. Unfallchirurg. 2016 Aug;119(8):648-53. doi: 10.1007/s00113-015-0110-z. German. PubMed PMID: 26537969.

15: Scheller B, Wicker S, Rabenau HF, Marzi I, Wutzler S. [Risk estimation of blood-borne infections by emergency room personnel]. Unfallchirurg. 2016 Jul;119(7):575-80. doi: 10.1007/s00113-014-2657-5. German. PubMed PMID: 25370501.

17: Ansaloni L, Pisano M, Coccolini F, Peitzmann AB, Fingerhut A, Catena F, Agresta F, Allegri A, Bailey I, Balogh ZJ, Bendinelli C, Biffl W, Bonavina L, Borzellino G, Brunetti F, Burlew CC, Camapanelli G, Campanile FC, Ceresoli M, Chiara O, Civil I, Coimbra R, De Moya M, Di Saverio S, Fraga GP, Gupta S, Kashuk J, Kelly MD, Koka V, Jeekel H, Latifi R, Leppaniemi A, Maier RV, Marzi I, Moore F, Piazzalunga D, Sakakushev B, Sartelli M, Scalea T, Stahel PF, Taviloglu K, Tugnoli G, Uraneus S, Velmahos GC, Wani I, Weber DG, Viale P, Sugrue M, Ivatury R, Kluger Y, Gurusamy KS, Moore EE. 2016 WSES guidelines on acute calculous cholecystitis. World J Emerg Surg. 2016 Jun 14;11:25. doi: 10.1186/s13017-016-0082-5. eCollection 2016. Review. Erratum in: World J Emerg Surg. 2016 Nov 4;11:52. PubMed PMID: 27307785; PubMed Central PMCID: PMC4908702.

18: Henrich D, Nau C, Kraft SB, Zollfrank M, Kontradowitz K, Oppermann E, Schultheiss J, Meier S, Frank J, Marzi I, Seebach C. Effect of the harvest procedure and tissue site on the osteogenic function of and gene expression in human mesenchymal stem cells. Int J Mol Med. 2016 Apr;37(4):976-88. doi: 10.3892/ijmm.2016.2489. Epub 2016 Feb 12. PubMed PMID: 26935410; PubMed Central PMCID: PMC4790676.

19: Lustenberger T, Kern M, Relja B, Wutzler S, Störmann P, Marzi I. The effect of brain injury on the inflammatory response following severe trauma. Immunobiology. 2016 Mar;221(3):427-31. doi: 10.1016/j.imbio.2015.11.011. Epub 2015 Nov 27. PubMed PMID: 26688509.

20: Relja B, Menke J, Wagner N, Auner B, Voth M, Nau C, Marzi I. Effects of positive blood alcohol concentration on outcome and systemic interleukin-6 in major trauma patients. Injury. 2016 Mar;47(3):640-5. doi: 10.1016/j.injury.2016.01.016. Epub 2016 Jan 28. PubMed PMID: 26850862.

2015

1: Leppik LP, Froemel D, Slavici A, Ovadia ZN, Hudak L, Henrich D, Marzi I, Barker JH. Effects of electrical stimulation on rat limb regeneration, a new look at an old model. Sci Rep. 2015 Dec 17;5:18353. doi: 10.1038/srep18353. PubMed PMID: 26678416; PubMed Central PMCID: PMC4683620.

2: Relja B, Horstmann JP, Kontradowitz K, Jurida K, Schaible A, Neunaber C, Oppermann E, Marzi I. Nlrp1 inflammasome is downregulated in trauma patients. J Mol Med (Berl). 2015 Dec;93(12):1391-400. doi: 10.1007/s00109-015-1320-0. Epub 2015 Aug 2. PubMed PMID: 26232934.

3: Kaufmann RA, Marzi I, Vogl TJ. Delayed diagnosis of isolated alar ligament rupture: A case report. World J Radiol. 2015 Oct 28;7(10):357-60. doi: 10.4329/wjr.v7.i10.357. PubMed PMID: 26516433; PubMed Central PMCID: PMC4620117.

4: Sander AL, Ebert F, Marzi I, Frank J. [Outcome after Implantation of the Aptis Total Distal Radioulnar Joint Replacement Prosthesis]. Handchir Mikrochir Plast Chir. 2015 Oct;47(5):306-11. doi: 10.1055/s-0035-1550035. Epub 2015 Jun 15. German. PubMed PMID: 26075895.

5: Lustenberger T, Wutzler S, Störmann P, Laurer H, Marzi I. The role of angio-embolization in the acute treatment concept of severe pelvic ring injuries. Injury. 2015 Oct;46 Suppl 4:S33-8. doi: 10.1016/S0020-1383(15)30016-4. PubMed PMID: 26542864.

6: Relja B, Weber R, Maraslioglu M, Wagner N, Borsello T, Jobin C, Marzi I, Lehnert M. Differential Relevance of NF-κB and JNK in the Pathophysiology of Hemorrhage/Resususcitation-Induced Liver Injury after Chronic Ethanol Feeding. PLoS One. 2015 Sep 14;10(9):e0137875. doi: 10.1371/journal.pone.0137875. eCollection 2015. PubMed PMID: 26367181; PubMed Central PMCID: PMC4569329.

7: Wutzler S, Lefering R, Wafaisade A, Maegele M, Lustenberger T, Walcher F, Marzi I, Laurer H; TraumaRegister DGU. Aggressive operative treatment of isolated blunt traumatic brain injury in the elderly is associated with favourable outcome. Injury. 2015 Sep;46(9):1706-11. doi: 10.1016/j.injury.2015.02.013. Epub 2015 Mar 1. PubMed PMID: 25799473.

8: Relja B, Omid N, Schaible A, Perl M, Meier S, Oppermann E, Lehnert M, Marzi I. Pre- or post-treatment with ethanol and ethyl pyruvate results in distinct anti-inflammatory responses of human lung epithelial cells triggered by interleukin-6. Mol Med Rep. 2015 Aug;12(2):2991-8. doi: 10.3892/mmr.2015.3764. Epub 2015 May 8. PubMed PMID: 25954992.

9: Seebach C, Henrich D, Schaible A, Relja B, Jugold M, Bönig H, Marzi I. Cell-based therapy by implanted human bone marrow-derived mononuclear cells improved bone healing of large bone defects in rats. Tissue Eng Part A. 2015 May;21(9-10):1565-78. doi: 10.1089/ten.TEA.2014.0410. Epub 2015 Apr 13. PubMed PMID: 25693739.

10: Voth M, Holzberger S, Auner B, Henrich D, Marzi I, Relja B. I-FABP and L-FABP are early markers for abdominal injury with limited prognostic value for secondary organ failures in the post-traumatic course. Clin Chem Lab Med. 2015 Apr;53(5):771-80. doi: 10.1515/cclm-2014-0354. PubMed PMID: 25324448.

11: Czerny C, Eichler K, Croissant Y, Schulz B, Kronreif G, Schmidt R, von Roden M, Schomerus C, Vogl TJ, Marzi I, Zangos S. Combining C-arm CT with a new remote operated positioning and guidance system for guidance of minimally invasive spine interventions. J Neurointerv Surg. 2015 Apr;7(4):303-8. doi: 10.1136/neurintsurg-2013-011034. Epub 2014 Mar 5. PubMed PMID: 24598402.

12: Vogl TJ, Frellesen C, Bauer RW, Kerl M, Zacharowski K, Marzi I, Hellwig T, Hammerstingl R, Lehnert T, Eichler K. Multidisciplinary sliding-gantry CT: from concept to reality. J Comput Assist Tomogr. 2015 Mar-Apr;39(2):290-4. doi: 10.1097/RCT.0000000000000199. PubMed PMID: 25580679.

13: Fischer S, Vogl TJ, Marzi I, Zangos S, Wichmann JL, Scholtz JE, Mack MG, Schmidt S, Eichler K. Percutaneous cannulated screw fixation of sacral fractures and sacroiliac joint disruptions with CT-controlled guidewires performed by interventionalists: single center experience in treating posterior pelvic instability. Eur J Radiol. 2015 Feb;84(2):290-4. doi: 10.1016/j.ejrad.2014.11.017. Epub 2014 Dec 3. PubMed PMID: 25523823.

14: Henrich D, Verboket R, Schaible A, Kontradowitz K, Oppermann E, Brune JC, Nau C, Meier S, Bonig H, Marzi I, Seebach C. Characterization of bone marrow mononuclear cells on biomaterials for bone tissue engineering in vitro. Biomed Res Int. 2015;2015:762407. doi: 10.1155/2015/762407. Epub 2015 Feb 23.

15: Eichler K, Marzi I, Wyen H, Zangos S, Mack MG, Vogl TJ. Multidetector computed tomography (MDCT): simple CT protocol for trauma patient. Clin Imaging. 2015 Jan-Feb;39(1):110-5. doi: 10.1016/j.clinimag.2014.09.011. Epub 2014 Oct 16. PubMed PMID: 25457538.

Klinik für Unfall-, Hand- und Wiederherstellungschiurgie